Silverman, Richard B.,

The organic chemistry of drug design and drug action. - Third edition / Richard B. Silverman, Northwestern University, Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Evanston, Illinois, USA, Mark W. Holladay, Ambit Biosciences Corporation, Departments of Drug Discovery and Medicinal Chemistry, San Diego, California, USA. - xviii, 517 pages : illustrations (some color) ; 29 cm

Includes bibliographical references and index.

Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.

9780123820303 (alk. paper) 0123820308 (alk. paper)

2013043146


Pharmaceutical chemistry.
Bioorganic chemistry.
Molecular pharmacology.
Drugs--Design.

RS403.S55 2014